Impact of a Targeted Nutritional Intervention on Glycaemic Variability and Correlation Between Glycaemic Parameters and Satiety.

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age12-18
SponsorHospices Civils de Lyon

About this trial

Obesity affects 18% of French adults and increasingly impacts adolescents. Dietary management is challenging, particularly with eating disorders like hyperphagia. The study hypothesizes that glycaemic variability contributes to eating disorders, as blood glucose fluctuations and reactive hypoglycaemia may exacerbate compulsive eating. Currently, no data exists on the relationship between glycaemic profile and satiety in obese adolescents.

This exploratory study will establish foundation for larger research evaluating glucose sensors as therapeutic education tools in obesity management, helping patients understand diet-satiety relationships.

Eligibility criteria

Qualifiers

Adolescents who have entered puberty (Tanner S2+ or G2+)

Aged over 12 and under 18 years

Obese, defined by an IOTF Body Mass Index (BMI) > 30

Child's assent and consent from the person(s) exercising parental authority

Disqualifiers

Type 2 diabetes: HbA1c > 6.5% or fasting plasma glucose > 1.26 g/L

Type 1 diabetes

Treatment capable of altering the glycemic profile (e.g., corticosteroids)

Intercurrent illness capable of significantly impacting eating behavior (e.g., Prader-Willi syndrome) or the postprandial glycemic profile

Trial design

Treatments tested in this trial

  • The primary intervention in this study is dietary counseling and education on adopting a low glycaemic index diet with sample menus provided
  • continuous glucose monitoring (CGM) sensors

Treatment groups

20 Participants
are divided into 1 treatment group

Sponsors and collaborators