Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age40-75
SponsorWashington University School of Medicine

About this trial

\- The investigators propose a clinical trial to evaluate the impact of annual shared decision making for PSA screening, supported by system-level enhancements to promote evidence-based care:

* Defined referral thresholds within the health maintenance reminder, aligned with clinical risk stratification per NCCN guidelines. * Enhanced clinical decision support (CDS) tools to reduce provider variation and ensure guideline-concordant screening and referral practices. * The goal is to reduce late-stage presentation without increasing overdiagnosis-ensuring that prostate cancer screening is both accessible and clinically effective.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Receive care within the BJC Health System

Have had at least one primary care physician appointment in the calendar year of PSA screening (primary care)

Be male

Not have a history of prostate cancer

Disqualifiers

None

Trial design

Design model

Single group

Treatments tested in this trial

  • Annual PSA Health Maintenance Reminder

    Other intervention

    The annual health maintenance reminder does not mandate PSA screening for eligible patients. Instead, it recommends that primary care providers (PCPs) initiate a shared decision-making discussion with their patients. As part of this conversation, patients will be informed of their individual risk factors-including race, family history, and germline mutations-and can then make an informed choice about whether to proceed with PSA screening.

Treatment groups

40,000 Participants
are divided into 1 treatment group
Group A: Annual PSA Health Maintenance ReminderExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Change in PSA screening completion rates in the BJC East Health System

The overall PSA screening rate will be calculated as the number of PSA screening tests that are ordered by PCPs who will receive the alert and completed by patients within a year of the ordering date, divided by the total number of eligible patients.

Time frame
Through 5 years

Secondary outcomes

1

Proportion of men diagnosed with clinically significant prostate cancer (Gleason score ≥ 7)

Time frame
Through 5 years
2

Incidence of advanced and metastatic disease at diagnosis of prostate cancer

Time frame
Through 5 years
3

Incidence of early-stage prostate cancer

Time frame
Through 5 years
4

Stage distribution of prostate cancer diagnoses

Time frame
Through 5 years

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.