Impact of Chewing Gum on Postoperative Gut Motility in Gastrointestinal Surgery Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age17-85
SponsorKhyber Medical University Peshawar
About this trial
Postoperative ileus (POI) is a frequent complication after abdominal surgery, leading to delayed gastrointestinal motility, prolonged hospital stay, and increased patient discomfort. Chewing gum, as a form of sham feeding, has been proposed to stimulate gut motility through vagal stimulation and increased gastrointestinal secretions. This randomized controlled trial aims to assess the effect of chewing gum on early recovery of gastrointestinal motility in patients undergoing open gastrointestinal surgery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age between 17 and 85 years.
Patients of either gender.
Undergoing open gastrointestinal surgical procedures (elective or emergency).
Willing to participate and able to provide informed consent.
Disqualifiers
Patients with metabolic or endocrine disorders (diabetes mellitus, hypothyroidism, or hyperthyroidism).
Patients with renal disease or electrolyte imbalance.
Patients with chronic constipation or neuromuscular disorders.
Patients with substance abuse or drug addiction.
Trial design
Design model
Parallel
Treatments tested in this trial
Chewing Gum
BehavioralParticipants will chew glucose/carbohydrate-containing chewing gum for 15 minutes, three times daily, starting 6 hours after surgery and continuing for 48 hours or until the first passage of flatus or stool, in addition to standard postoperative care.
Treatment groups
96 Participants
are divided into 2 treatment groupsGroup A: Chewing Gum Intervention GroupExperimental treatment 1 intervention
Group B: Standard Care Control GroupNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Time to First Passage of Flatus
Time interval (in hours) from the end of surgery to the first postoperative passage of flatus, assessed by patient self-report and clinical evaluation.
Time frame
Within 48 hours postoperatively2
Time to First Defecation
Time interval (in hours) from the end of surgery to the first postoperative bowel movement (defecation), assessed by patient self-report and clinical evaluation.
Time frame
Within 48 hours postoperativelySponsors and contacts
Click on the lead sponsor to view all of their trials.
Khyber Medical University Peshawar
Lead sponsor
Khyber Teaching Hospital
Collaborator
Source ClinicalTrials.gov