Impact of Combined Intravenous-Inhalational vs Inhalational Anesthesia on QoR-15 Recovery Scores in Gynecologic Surgery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorSakarya University
About this trial
This study aims to compare the effects of combined intravenous-inhalational anesthesia versus inhalational anesthesia alone on postoperative recovery in patients undergoing elective gynecologic surgery.
A total of 100 patients, aged 18-65 years and classified as ASA I-III, scheduled for elective gynecologic procedures at Sakarya University Faculty of Medicine Training and Research Hospital, will be included. The sample size was calculated based on the primary outcome, the Quality of Recovery-15 (QoR-15) score.
Patients will complete the QoR-15 questionnaire preoperatively, before knowing which anesthesia method will be applied. Postoperative QoR-15 scores will be collected on postoperative days 1 and 2, and intraoperative data will be obtained from anesthesia records.
The study evaluates postoperative recovery using QoR-15 scores, covering physical comfort, emotional state, psychological support, pain, and ability to perform daily activities. Higher scores indicate better recovery, whereas lower scores indicate impaired postoperative recovery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients aged 18-65 years
Scheduled for elective gynecologic surgery at Sakarya University Faculty of Medicine Training and Research Hospital
Classified as ASA I-III
Able to understand and complete the QoR-15 questionnaire
Disqualifiers
Severe comorbidities (beyond ASA III)
Patients with advanced neurological disease or cognitive impairment
Known allergy to anesthetic drugs used in the study
Classified as ASA IV-V
Trial design
Design model
Parallel
Treatments tested in this trial
Combined Intravenous-Inhalational Anesthesia
DrugPatients will receive a combination of intravenous anesthetic agents and inhalational anesthetic gases during elective gynecologic surgery. The specific anesthetic drugs and doses will follow routine clinical practice. Postoperative recovery will be assessed using the Quality of Recovery-15 (QoR-15) questionnaire on postoperative days 1 and 2.
Inhalational Anesthesia Only
DrugPatients will receive only inhalational anesthetic gases during elective gynecologic surgery, following routine clinical practice. Postoperative recovery will be assessed using the QoR-15 questionnaire on postoperative days 1 and 2.
Treatment groups
100 Participants
are divided into 2 treatment groupsGroup A: Combined Intravenous-Inhalational AnesthesiaExperimental treatment 1 intervention
Group B: Inhalational Anesthesia OnlyActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Postoperative recovery using QoR-15
Postoperative recovery will be assessed using the Quality of Recovery-15 (QoR-15) questionnaire, a validated patient-reported outcome measure. The questionnaire evaluates physical comfort, emotional state, psychological support, pain, and ability to perform daily activities. Higher scores indicate better recovery.
Time frame
Postoperative Day 1 and Postoperative Day 2Secondary outcomes
1
Postoperative pain score
Pain will be assessed using a standard numerical rating scale (0-10) at postoperative hours 6, 12, and 24. Higher scores indicate more pain.
Time frame
Postoperative hours 6, 12, and 242
Postoperative nausea and vomiting (PONV) incidence
Incidence of nausea and vomiting will be recorded in the first 24 hours after surgery.
Time frame
Postoperative hours 0-243
Length of stay in post-anesthesia care unit (PACU)
Duration of stay in PACU will be recorded in minutes from admission to discharge.
Time frame
Postoperative period (PACU stay), assessed up to 10 daysSponsors and contacts
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Source ClinicalTrials.gov