Severe rhabdomyolysis is a common medical emergency that can lead to acute kidney injury (AKI), sometimes requiring extracorporeal renal replacement therapy (ECRT). Myoglobin plays a major role among the molecules involved in nephrotoxicity. While ECRT techniques are commonly used in this situation, their actual effectiveness in eliminating myoglobin and improving renal function remains poorly established. In particular, mid-cut-off membranes, developed to better remove intermediate molecular weight molecules, could improve renal prognosis. This study aims to evaluate, using retrospective clinical data, the impact of these techniques on renal recovery.
Adult patient (≥18 years).
Patient is hospitalized in the nephrology or medical intensive care units of the Strasbourg University Hospitals (NHC or Hautepierre) between 2015 and 2024.
Confirmed diagnosis of severe rhabdomyolysis associated with acute kidney injury, with or without renal replacement therapy.
Patient has not objected to the reuse of their medical data.
Patient has objected to the reuse of their data.
Incomplete medical file preventing the complete analysis of the data necessary for the study.
Subject under guardianship, curatorship, or legal protection.
Adult patient (≥18 years) with confirmed diagnosis of severe rhabdomyolysis associated with acute kidney injury, with or without renal replacement therapy.
Case-only
Retrospective
Not listed
Total duration of dependence on extrarenal purification (ERP) (in days)
Total duration of dependence on ERC (in days), defined as the number of days between initiation and discontinuation of any form of dialysis.
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