Impact of Frailty and ICU-AW on Post-ICU Fatigue Self-reported

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre Hospitalier Universitaire de Saint Etienne

About this trial

After a prolonged stay in Intensive Care Unit (ICU), fatigue is the most common symptom reported by patients in the Post Intensive Care Syndrome (PICS). Other complications have been described, including ICU-acquired weakness, leading to increased morbidity and mortality after discharge. Actually, risk factors associated with post-ICU fatigue self-reported are not really known.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with a length of stay in intensive care > or equal to 7 days, or mechanical ventilation > or equal to 5 days

Disqualifiers

Scheduled surgery with admission in ICU

Pregnancy

Guardianship

Trial population

Patients admitted to intensive care, all etiologies combined, excluding immediate post-operative scheduled surgery, with mechanical ventilation for more than 5 days or length of stay in ICU over 10 days.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • observational prospective data collection

    Other intervention

    Collection of data from medical records.

Treatment groups

150 Participants
are divided into 1 treatment group
Group A: Patients on etiologies1 intervention

Trial outcomes

Primary outcomes

1

Frailty

Relationship between frailty markers (CFS, IADL, sarcopenia and myosteatosis), ICU-AW, ICU story and post-ICU fatigue self-reported

Time frame
1 year

Secondary outcomes

1

Fatigue

Prevalence of post-ICU fatigue self-reported 6 months discharge in prospective cohort

Time frame
1 year
2

ICU-acquired weakness and fatigue

Correlation between post-ICU fatigue self-reported and muscular strength assessed by handgrip test

Time frame
1 year
3

Fatigue, quality of life, anxiety and depressive disorder

Correlation between fatigue, quality of life, anxiety and depressive disorder

Time frame
1 year
4

Kinetic of muscle mass loss and post-ICU fatigue self-reported

Correlation between the kinetic of muscle mass loss and post-ICU fatigue self-reported

Time frame
1 year

Other outcomes

Sponsors and contacts

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