This prospective observational study aims to evaluate the association between intraoperative perfusion variability and postoperative troponin elevation in geriatric patients undergoing major oncologic surgery. Intraoperative hemodynamic and perfusion-related parameters will be recorded, and postoperative troponin levels will be assessed to investigate whether intraoperative perfusion changes are associated with myocardial injury. Troponin measurements will be obtained preoperatively and at 24 hours after surgery
Age 65 years or older
Undergoing major abdominal oncologic surgery
Availability of preoperative and 24-hour postoperative troponin measurements
Complete intraoperative and postoperative patient monitoring records
Age younger than 65 years
Absence of preoperative or 24-hour postoperative troponin measurements
Incomplete intraoperative or postoperative patient monitoring records
Undergoing emergency surgery
Geriatric patients aged 65 years or older undergoing major abdominal oncologic surgery who meet the predefined eligibility criteria and have preoperative and 24-hour postoperative troponin measurements. Intraoperative hemodynamic and perfusion parameters, including PI, PVI, and cerebral oxygen saturation measured by NIRS, will be monitored throughout surgery and recorded at 15-minute intervals.
Cohort
Prospective
Not listed
Change in Serum Troponin Concentration From Preoperative Baseline to 24 Hours After Surgery
Postoperative troponin elevation will be assessed by comparing serum troponin levels measured preoperatively and 24 hours after surgery. Its association with intraoperative perfusion variability will be evaluated.
Association Between Intraoperative Perfusion Index and Postoperative Troponin Elevation
Perfusion Index (PI) will be continuously monitored intraoperatively and recorded at 15-minute intervals. The association between intraoperative PI values and postoperative troponin elevation at 24 hours after surgery will be evaluated.
Association Between Intraoperative Pleth Variability Index and Postoperative Troponin Elevation
Pleth Variability Index (PVI) will be continuously monitored intraoperatively and recorded at 15-minute intervals. The association between intraoperative PVI values and postoperative troponin elevation at 24 hours after surgery will be evaluated.
Association Between Intraoperative Cerebral Oxygen Saturation and Postoperative Troponin Elevation
Cerebral oxygen saturation measured by near-infrared spectroscopy (NIRS) will be continuously monitored intraoperatively and recorded at 15-minute intervals. The association between intraoperative cerebral oxygen saturation values and postoperative troponin elevation at 24 hours after surgery will be evaluated.
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