The purpose of this study is to compare the effect of a single dose of 8 mg of intravenous dexamethasone versus placebo on the duration of sensory and motor block after spinal anesthesia with chloroprocaine.
Age between 18 and 90 years old
ASA status I to III inclusively
Planned lower body surgery under spinal anesthesia with chloroprocaine
Signed informed consent form
Contraindication to spinal anesthesia: infection at the puncture site, congenital or acquired coagulopathy
Preexisting neuropathy or nerve block that could interfere with study assessments
Allergy or hypersensitivity to local anesthetics, dexamethasone, or other medications used in the study
Preoperative use of corticosteroids
Parallel
Intravenous Dexamethasone
DrugAdministration of a single-dose of intravenous dexamethasone 8 mg during spinal anesthesia with chloprocaine
Normal Saline
DrugAdministration of a single-dose of Normal saline during spinal anesthesia with chloprocaine
Regression of sensory block by 2 dermatomes
Loss of pinprick sensation by Von Frey filaments from the injection of chloroprocaine for spinal anesthesia until regression of the sensory block by two dermatomes from the peak sensory level
Duration of motor block
Using the Bromage scale from the time of injection of chloroprocaine for spinal anesthesia until complete recovery of motor block
Time until the first observable regression of the motor block
Time between the local anesthesic injection and the first measurable regression of the motor block measured using the Bromage scale.
Onset of sensory block
Time from injection of chloroprocaine for spinal anesthesia to reduction of sensitivity using loss of pinprick sensation
Onset of motor block
Time from injection of chloroprocaine for spinal anesthesia to reduction of lower limbs movement using the Bromage scale
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