About this trial
This prospective, multicenter randomized controlled trial aimed to investigate whether linked color imaging (LCI) could reduce the miss rate of sessile serrated lesions (SSLs) during tandem colonoscopy compared with conventional white-light imaging (WLI).
Eligibility criteria
Qualifiers
Subjects aged ≥45 years, regardless of gender;
Subjects undergoing screening colonoscopy;
Subjects with no prior colonoscopy;
Voluntarily provide written informed consent.
Disqualifiers
Subjects unable to cooperate with or tolerate colonoscopy;
Subjects with inflammatory bowel disease;
Known or highly suspected colorectal obstruction;
History of colorectal surgery;
Trial design
Treatments tested in this trial
- WLI Then LCI Withdrawal
- LCI Then WLI Withdrawal
Treatment groups
Locations
Sponsors and collaborators
Nanfang Hospital, Southern Medical University
Lead sponsor
Shunde First People's Hospital of Foshan
Collaborator
ZhuHai Hospital
Collaborator
Jiangmen Central Hospital
Collaborator
Yangjiang People's Hospital
Collaborator
Zhongshan Guzhen People's Hospital
Collaborator
Sihui Wanlong Hospital
Collaborator
The Third People's Hospital of Huizhou
Collaborator
Longgang District People's Hospital of Shenzhen
Collaborator
Suixi People's Hospital of Zhanjiang
Collaborator