About this trial
chemical pleurodesis using doxycycline is an acceptable and commonly employed palliation for malignant pleural effusion. Rotation of patient during pleurodesis using the powder from doxycycline capsule is still practiced in some centers. The benefit of rotation practice in pleurodesis can be verified after properly designed study on the outcome of pleurodesis with rotation and non-rotation by chest ultrasound assessment
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients who will be admitted at Chest department, Ain-Shams University Hospitals with malignant pleural effusions candidate for pleurodesis
Disqualifiers
Multiloculated fluid
Previous failed pleurodesis
Liver failure
Renal failure
Trial design
Parallel
Treatments tested in this trial
side to side and front to back rotation 30 minutes each
Other interventionside to side and front to back rotation 30 minutes each after pleurodesis
Treatment groups
Trial outcomes
Primary outcomes
Measurement of pleural adhesion score in patients with malignant pleural effusion candidates for pleurodesis in group with rotation and the other without rotation
study how patient rotation after pleurodesis affects its success by measuring pleural adherence score by chest ultrasound, a higher adhesion score means successful pleurodesis
Secondary outcomes
Measurement of non-verbal Pain score in patients with malignant pleural effusion candidates for pleurodesis in group with rotation and the other without rotation
Estimation of non-verbal pain score in patients with and without rotation after pleurodesis to assess how this rotation affects patients' comfort. A higher pain score means less comfort.
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