Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Surgical Valve Replacement Patients
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorOdense University Hospital
About this trial
In Odense University Hospital preoperative dental screening (PDS) protocol for patients treated with surgical valve replacement was changed from mandatory to targeted PDS to from march 2024.
The investigators will therefore compare the risk of IE before vs after march 2024.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients undergoing surgical valve replacement
Disqualifiers
None
Trial population
All patients undergoing surgical valve replacement from March 2024 to March 2027 from Odense University Hospital compared with same type of patients from the same center from the period January 2020 to March 2024.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
No preoperative dental screening
Procedure/SurgeryDiscontinuance of mandatory preoperative dental screening prior surgical valve replacement which also can include oral surgery.
Treatment groups
1,000 Participants
are divided into 2 treatment groupsGroup A: No preoperative dental screening1 intervention
Group B: Mandatory preoperative dental screening0 interventions
Trial outcomes
Primary outcomes
1
Number of Participants with Infectious Endocarditis
Infectious endocarditis diagnosed by healthcare professionals
Time frame
Through study completion, an average of 1 yearSecondary outcomes
1
Number of Participants undergoing Oral surgical procedure at dental screening
Number of oral surgical procedure performed in patients as part of the dental screening
Time frame
Through study completion, an average of 1 year2
Number of Participants undergoing Tooth extraction at dental screening
Number of Tooth extraction procedure performed in patients as part of the dental screening
Time frame
Through study completion, an average of 1 year3
The different Bacteria types causing the infectious endocarditis assessed by blood culture
Reporting all the different bacteria type causing infectious endocarditis, including the rate of each bacteria.
Time frame
Through study completion, an average of 1 year4
Number patients with Bacteremia assessed by positive blood culture
Cases of bacteremia in the population
Time frame
Through study completion, an average of 1 yearSponsors and contacts
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Source ClinicalTrials.gov