The objective of this randomized monocentric study is to assess potential variations in the incidence and severity of isthmocele morbidity among women undergoing cesarean section with either single or double-layer closure of the hysterotomy. Our primary outcome aims to investigate whether there is a reduction in the median duration of intermenstrual spotting in patients belonging to the two respective closure groups
nulliparous
singleton
age 18-45
spontaneous pregnancy or autologous assisted fertilization
coagulopathy
autoimmune diseases
gestational diabetes
anticoagulant therapy
Single group
Hysterotomy closure
Procedure/SurgeryHysterotomy closure is done in either one of two ways. Single layer closure consists in a single layer, unlocked suture. Double layer closure consists in a double layer, unlocked suture.
Intermenstrual bleeding reduction (days)
The primary outcome of the study is to evaluate weather there is a reduction of intermenstrual bleeding in the six months after cesarean section among the two groups of patients.
Intra-operatory time
Evaluate evaluate weather there is a difference in operative time among the two groups of patients
Blood loss
Evaluate any difference in intra-operative blood loss (milliliters of blood)
Analgesics
Evaluate any difference in post-operative use of analgesics
Post-operatory recovery time
Evaluate any difference in post-operative recovery time (days)
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