Impact of Subclinical Hypothyroidism on Liver Enzymes and Lipid Profile

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorAssiut University

About this trial

the goal of the randomized controlled observational study is to observe the effect of subclinical hypothyroidism on liver enzymes and lipid profile

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

• Age ≥ 18 years

For SCH group: Elevated TSH with normal FT4

For control group: Normal TSH and FT4 levels

Disqualifiers

• Evident hypothyroidism or hyperthyroidism

Diagnosed with diabetes mellitus

Chronic liver disease

Chronic kidney disease

Trial population

internal medicine department

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • liver enzymes

    Diagnostic test

    subclinical hypothyroidism on liver enzymes and lipid profile

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Impact of Subclinical Hypothyroidism on Liver Enzymes and Lipid Profile

1. Mean levels of liver enzymes (ALT, AST, GGT) • To determine whether there is a statistically significant difference in liver enzyme levels between individuals with subclinical hypothyroidism and euthyroid controls. 2. Mean values of lipid profile components (Total Cholesterol, LDL-C, HDL-C, Triglycerides) • To assess whether subclinical hypothyroidism is associated with dyslipidemia compared to the control group.

Time frame
Baseline

Secondary outcomes

Other outcomes

Sponsors and contacts

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