About this trial
With this study, the investigators want to investigate how deep brain stimulation (DBS) affects various cognitive and psychiatric symptoms of Parkinson's disease (PD). In particular, they will examine whether stimulation of the left hemisphere has a different effect than stimulation of the right hemisphere on cognitive and psychiatric symptoms.
Eligibility criteria
Qualifiers
Diagnosed with Parkinson's disease
Treated with subthalamic nucleus deep brain stimulation (STN-DBS)
For part I: General research consent for the analysis of routine clinical data
For part II of the study: ability to provide informed consent
Disqualifiers
Atypical Parkinsonism
Other disease affecting the brain (e.g. Alzheimer's disease, vascular dementia, multiple sclerosis, stroke, traumatic brain injury, non-provoked epilepsy, brain tumour, etc.)
Haemorrhage during implantation of STN-DBS, which resulted in permanent cognitive or physical impairment
Schizophrenia, ongoing substance abuse, bipolar disorder or autism
Trial design
Treatments tested in this trial
- DBS OFF state for left hemisphere
- DBS OFF state for right hemisphere