Health TrialsbyHealthPanel

Impact of Surgical Approach on Adaptation of Posture-respiratory Coupling

ConditionResectable Lung Non-Small Cell Carcinoma
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris

About this trial

This study aims to identify physiopathologic mechanisms related to surgical approaches during lobectomies for non-small cell lung cancer which can explain the better quality of life and the decrease of of post-operative complications in minimally invasive techniques (video-assisted thoracic surgery and robotic-assisted thoracic surgery) compared to conventional thoracotomy.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients admitted for major lung resection

Surgical approach by conventional postern-lateral thoracotomy

Surgical approach by minimally invasive RATS

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • EOS imaging for musculoskeletal disorder

    Other intervention

    The patients will have a low radiation 2D/3D biplane imaging of the rib cage, and spine before and after surgery.

  • Movement analysis by an optoelectronic camera.

    Other intervention

    Movement analysis by an optoelectronic camera before and after surgery.

  • Stabilometric measurement by strength platform

    Other intervention

    Stabilometric measurement by strength platform before and after surgery.

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: ThoracotomyActive comparator 3 interventions
Group B: RATS (robotic-assisted thoracoscopic surgery)Active comparator 3 interventions

Trial outcomes

Primary outcomes

1

Thoracic kyphosis (T1- T12 angle) and vertical alignment head-pelvis and head- C7 vertebra (angle OD-HA and OD-C7) (EOS)

Variation between pre- and post-operative measurement

Time frame
Assessment one week before surgery and 4 weeks surgery.

Secondary outcomes

1

Width of rib cage (EOS)

Variation between pre- and post-operative measurement in centimeters

Time frame
Assessment one week before surgery and 4 weeks after surgery.
2

Rib cage volume (EOS)

Variation between pre- and post-operative measurement in Liter

Time frame
Assessment one week before surgery and 4 weeks after surgery.
3

" Umbrella "angle (EOS)

Variation between pre- and post-operative measurement

Time frame
Assessment one week before surgery and 4 weeks after surgery
4

Center of Pressure displacement (Optoelectronic system)

Variation between pre- and post-operative measurement

Time frame
Assessment one week before surgery and 4 weeks after surgery

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assistance Publique - Hôpitaux de Paris

Lead sponsor

Source ClinicalTrials.gov
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