Impact of the Procurement Technique on Outcomes After Liver Transplantation

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris

About this trial

Liver transplantation (LT) is the standard treatment for hepatocellular carcinoma (HCC) and end-stage liver disease, with excellent long-term outcomes despite the increasing use of extended criteria donors due to organ shortage. As traditional evaluation criteria have become insufficient, new indicators such as Arterial and Biliary Complication-Free Survival (ABCFS) have been developed to better assess post-transplant outcomes.

Primary objective: To assess, in a large-scale study, whether the procurement technique influences liver transplantation outcomes in terms of arterial and biliary complication-free survival.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients aged 18 years or older at the time of inclusion

Listed on the national waiting list of the Agence de la Biomédecine (ABM)

Undergoing a first liver transplantation in France

Receiving a whole liver graft

Disqualifiers

Pancreas procurement

Multiorgan transplantation

Split liver transplantation (shared grafts)

Retransplantation

Trial population

adult patients (≥18 years) who undergo a first liver transplantation in France.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Arterial and Biliary Complication-Free Survival (ABCFS) at 3 years

Time frame
at 3 years post-transplantation

Secondary outcomes

1

Postoperative complications at 90 days

Time frame
at 90 days post-transplantation
2

Type of Biliary complications

Time frame
Up to 3 years post-transplantation
3

Type of Arterial complications

Time frame
Up to 3 years post-transplantation
4

Occurrence of vascular injuries observed following organ procurement

Time frame
Peri-procedural period (during procurement and immediately post-procurement)

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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