Title: Impact on quality of life and disease burden in adults with herpes zoster
Prospective cohort study for the primary objective and the secondary objectives (1 and 2) and retrospective cohort study for the secondary objective 3.
Disease or disorder under study: Patients with a herpes zoster (HZ) diagnosis.
None
Pregnant women
Patients with altered level of consciousness (dementia and others) who do not complete the questionnaires
Patients who do not wish to participate in the study 5.2 Retrospective cohort study Inclusion criteria Adults >18 years of age with a diagnosis of HZ in the CMBD from 2012 to 2023 at the Jiménez Díaz Foundation hospital. Since the international classification of diseases changed from ICD 9 to ICD 10 in 2106, the codes to be used for the inclusion of patients in the study are described below.
Herpes zoster
Prospective study: Patients \> 18 years of age who are to be immunized against HZ Retrospective study: Adults over 18 years of age with a diagnosis of HZ in the CMBD from 2012 to 2023 at the Jiménez Díaz Foundation hospital. Since the international classification of diseases changed from ICD 9 to ICD 10 in 2016, the codes to be used for the inclusion of patients in the study are described below. Patients diagnosed with herpes zoster (HZ). Study Population and Total Number of Patients: Based on the sample calculation, it is intended to include a total of 357 patients in the prospective study and 1,920 patients in the retrospective study.
Cohort
Prospective
Not listed
Quality of life of patients with a history of herpes zoster who attend the immunization unit of the Jiménez Díaz Foundation University Hospital.
Measuring the quality of life of patients with a history of herpes zoster who attend the immunization unit of the Jiménez Díaz Foundation University Hospital.
Quality of life according to the location of herpes zoster
Evaluate quality of life according to the location of herpes zoster (postherpetic neuralgia, ophthalmic zoster, etc.)
Effectiveness of the vaccine against herpes zoster
Evaluating the effectiveness of the herpes zoster vaccine in terms of the number of episodes, severity and quality of life.
Economic impact and disease burden in terms of morbidity and mortality
Economic impact and burden of disease in terms of morbidity and mortality of adult patients with herpes zoster
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