Impacts and Mechanisms of Age and Muscle Fatigue on Postural Control and Force Control
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20-85
SponsorChang Gung Memorial Hospital
About this trial
Muscle fatigue is one of the clinical symptoms in elderly people and demonstrates task dependency and muscle dependency. Muscle fatigue has been shown to negatively impact postural control, physical activity, and quality of life. However, the evidence for the influence of muscle fatigue on postural control is limited and inconsistent in elderly people. Therefore, this study aims to investigate the impacts of aging and muscle fatigue on postural control and gait performance with fatiguing exercises of upper and lower extremities.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
20 to 40 years (young), and 60-85 years (old)
walk independently
able to follow commands (Mini Mental Status Exam (MMSE) scores greater than 21
able and willing to provide informed consent.
Disqualifiers
pregnancy
neurologic, psychiatric, cardiac, vascular, pulmonary, musculoskeletal, immune, integumentary disease or disorder which might influence this study
any current loss of sensation in the arms, wrists, hands, fingers, hips, knees, ankles or toes
any pain at the time of testing
Trial population
This study recruits healthy elderly individuals and healthy young individuals
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
Age
Other interventionWe compare the young and the old groups
Muscle fatigue
Other interventionWe compare the results before and after muscle fatigue
Treatment groups
140 Participants
are divided into 1 treatment groupGroup A: Healthy people2 interventions
Trial outcomes
Primary outcomes
1
Maximal force
The maximal force of upper and lower extremity muscles
Time frame
Baseline (pre-fatigue protocol) and immediately after the fatigue protocol2
Walking speed
The time taken by participants to walk a standardized distance
Time frame
Baseline (pre-fatigue protocol) and immediately after the fatigue protocol3
Step Length
The linear distance between the two ankles, typically expressed in centimeter(cm).
Time frame
Baseline (pre-fatigue protocol) and immediately after the fatigue protocol4
Cadence
The number of steps taken per minute (SPM)
Time frame
Baseline (pre-fatigue protocol) and immediately after the fatigue protocolSecondary outcomes
1
Oxygenated hemoglobin
Oxygenated hemoglobin is the amount of hemoglobin bound to oxygen, reflecting tissue oxygen availability. It's expressed as the percentage.
Time frame
Baseline (pre-fatigue protocol), during the fatigue protocol, and immediately after the fatigue protocol.2
Total hemoglobin
Total hemoglobin is the combined amount of oxygenated and deoxygenated hemoglobin, reflecting overall blood volume in the tissue.
Time frame
Baseline (pre-fatigue protocol), during the fatigue protocol, and immediately after the fatigue protocol.3
Deoxygenated hemoglobin
Deoxygenated hemoglobin is the amount of hemoglobin not bound to oxygen, reflecting oxygen extraction by tissues. It's expressed as the percentage.
Time frame
Baseline (pre-fatigue protocol), during the fatigue protocol, and immediately after the fatigue protocol.Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Chang Gung Memorial Hospital
Lead sponsor
Chang Gung University
Sponsor institution
Chang Gung University
Collaborator
Source ClinicalTrials.gov