Implementation and Effectiveness of the BJC-Pink and Pearl Project on Lung Cancer Screening

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorWashington University School of Medicine

About this trial

The investigators proposal is ripe for executing as the investigators seek to leverage this "natural experiment" initiated by the BJC health system to evaluate the effectiveness of the Pink \& Pearl Campaign as an implementation strategy to promote lung cancer screening (LCS) uptake among LCS-eligible women undergoing mammography at BJC West County. This evaluation is grounded in the Integrated Screening Action Model that depicts individual- and environmental-level influences on the screening behavior process. Using an explanatory sequential mixed methods design, which combines both quantitative and qualitative approaches, the research questions and specific aims for this proposal are to: a) evaluate the baseline prevalence of LCS among LCS-eligible women; b) assess whether the Pink \& Pearl Campaign increases referrals and uptake/ completion of LCS among LCS-eligible women undergoing screening mammography; and c) evaluate individual and environmental factors influencing LCS uptake, and implementation outcomes of the campaign. These implementation outcomes will help identify whether the campaign was put in place successfully or not. This proposal will inform strategies for integrating cancer screening programs to improve poorly performing programs like LCS.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Undergoing screening mammography

Between the ages of 50-80 years (inclusive)

Reporting a 20 pack-year equivalent of either current smoking history or have quit in the past 15 years

Can speak and understand English

Disqualifiers

Diagnosed with a serious health problem that will likely limit life expectancy (such as previous history of lung cancer, symptoms of lung cancer such as hemoptysis or unexplained weight loss of more than 6.8 kg (15 lb) in the previous year)

Subjects with symptoms of lung cancer should get a diagnostic CT scan

Unable or unwilling to get treatment if lung cancer is found

Older than 20 years of age

Trial population

Women within the BJC West County electronic health record (EHR) who are scheduled to undergo screening mammography and are eligible for LCS, based on 2021 USPSTF guidelines. In addition to patients, healthcare providers involved in the breast radiology service who referred women to the Pink and Pearl project will also be included as study participants for the qualitative in-depth interviews. This group may include medical doctors, nurse practitioners, nurses, nurse navigators, and physician assistants. Up to 15 healthcare providers will be interviewed.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

279 Participants
are grouped into 2 trial groups
Group A: Participants - scheduled for mammography and eligible for LCS
Group B: Providers

Trial outcomes

Primary outcomes

1

Prevalence of LCS-eligible women who opt-in to, and successfully, complete LCS mammography and opt-in to lung cancer screening

Time frame
At baseline
2

Number of women screened for LCS

Time frame
At 3 months
3

Number of women screened for LCS

Time frame
At 6 months
4

Feasibility of Pink and Pearl project

Feasibility is defined as the extent to which the strategy is suitable for routine use in a setting. Information on the feasibility of the Pink and Pearl campaign from healthcare providers will be collected using in-depth interviewing.

Time frame
At 6 months

Secondary outcomes

1

Median time to lung cancer screening

Time frame
Through completion of follow-up (estimated to be 1 year)
2

Number of women who have a positive lung radiology screening

Time frame
Through completion of follow-up (estimated to be 1 year)
3

Rate of follow-up for a positive screening examination

Time frame
Through completion of follow-up (estimated to be 1 year)
4

False positive rates

Time frame
Through completion of follow-up (estimated to be 1 year)

Other outcomes

Sponsors and contacts

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