Improve Cancer-related Cognitive Impairment
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-90
SponsorUniversity of Alabama at Birmingham
About this trial
Cancer-related cognitive impairment (CRCI), also known as "chemobrain," is the cognitive decline that negatively impacts the majority of cancer patients undergoing chemotherapy, radiation, and/or hormonal treatments. This application focuses on evaluating if using a cognitive mobile training application can decrease the impact of CRCI in gynecologic oncology patients through a multidisciplinary approach with patients undergoing assessments by our neurocognitive team.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
newly diagnosed gynecologic malignancy (uterine, cervical, ovarian, primary peritoneal, vulvar, or vaginal) and undergoing chemotherapy
own a smartphone or tablet with ability to download cognitive training application
and age >21 years old
Disqualifiers
medical diagnosis of dementia
significant underlying mental diagnoses for which they are on more than 1 medication for (patients with depression or anxiety on single-agent therapy will be able to participate
age <21
Trial design
Design model
Parallel
Treatments tested in this trial
Cognitive training application
DevicePatients will participate with a cognitive training application and undergo neurocognitive testing during and after chemotherapy.
Treatment groups
64 Participants
are divided into 2 treatment groupsGroup A: OBSERVATIONNo intervention 0 interventions
Group B: MOBILE COGNITIVE TRAINING APPExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Neurocognitive function
Evaluated by the NIH Toolbox of Assessment of Neurologic Behavioral Function
Time frame
From initiation of chemotherapy through 2 years2
Neurocognitive function
Evaluated by the FACT-Cog survey
Time frame
From initiation of chemotherapy through 2 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov