Improving Availability of Intranasal Naloxone

ConditionOpioid Overdose

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age21-65

SponsorHartford Hospital

About this trial

While there is a lifesaving medication called naloxone that can reverse the deadly effects of opioid overdose, patients often fail to fill the prescription at the pharmacy when it is prescribed. This is particularly concerning and true in those at the highest risk of death-those who end up in the emergency department for opioid overdose. The goal of this study is to compare the impact of different overdose education on naloxone prescription fill rates in opioid users being discharged from our hospital emergency department. You will receive either (a) written education about naloxone through their MyChart account, or (b) a concise one-page handout and 4-minute video clip reviewed with the participant and a support individual (family/friend) prior to discharge.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Patient has previously received the standard naloxone kit education or has a known allergy to naloxone and/or kit constituents

Patient or support network does not speak English

Patient is in police custody

Patient is not being discharged home from the ED.

Trial design

Design model

Parallel

Treatments tested in this trial

Enhanced Overdose Education (EOE)
Behavioral
EOE was adapted by Co-I Dr. Monique Miley at HHC's premier addiction hospital-The Rushford Center. It follows the guidelines set by Co-PI Jonathan Craig Allen when working with opioid patients reluctant to obtain naloxone: * Express confidence in naloxone * Provide a clear statement about suitability (You are an excellent candidate for naloxone) * Begin discussion using presumptive language (You must be ready for an overdose)
Standard education
Behavioral
Written instructions that accompany a kit prescription in many EDs throughout the country.

Treatment groups

84 Participants

are divided into 2 treatment groups

Group A: Standard educationActive comparator 1 intervention

Group B: Enhanced Overdose Education (EOE)Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

Prescription fill rate

Pharmacy records/survey to determine if naloxone kit prescription was filled

Time frame

1 month

Secondary outcomes

Education content survey

Questionnaire measuring how much of education was retained and reasons for filling or not filling prescription

Time frame

1 month

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Hartford Hospital

Lead sponsor

Hartford HealthCare

Collaborator

Source ClinicalTrials.gov

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