Improving Cochlear Implant Outcomes Through Modeling and Programming Strategies Based on Human Inner Ear Pathology

ConditionDeafness
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorMassachusetts Eye and Ear Infirmary

About this trial

Cochlear implants are devices placed in the inner ear through surgery to help people with severe to profound hearing loss. While these devices work well overall, results vary widely from person to person. Many people with cochlear implants still have trouble understanding speech in noisy places and enjoying music.

This study looks at whether customizing the way a cochlear implant is programmed, based on the health of the hearing nerve in different areas of the ear, can help people understand speech better in noisy settings. The researchers will adjust or turn off certain electrodes in areas where the nerve appears weaker, then test whether this improves hearing compared to each person's everyday program. They will also examine whether giving people time to get used to the new program leads to better results.

Eligibility criteria

Qualifiers

Age 18 - 80 years old

Native speakers of American English or Multilingual

Wears a cochlear implant manufactured by Advanced Bionics (Clarion Hi-Focus I or newer)

At least 6 months of listening experience with their cochlear implant, but could be recruited and consented prior.

Disqualifiers

Inability to provide informed consent

Lost their hearing prior to the age of language acquisition (3-4 years) but did not receive a cochlear implant until adulthood

Do not have age-appropriate speech perception testing from clinical visits or do not use their implant for oral communication

Have neurological disease

Trial design

Treatments tested in this trial

  • Everyday Clinical Listening Program (Control)
  • ENI-Based Experimental Program 1
  • ENI-Based Experimental Program 2

Treatment groups

45 Participants
are divided into 1 treatment group

Locations

This trial has no locations