Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-100
SponsorBoston University Charles River Campus

About this trial

The investigators will evaluate the theory that Alzheimer's disease-related memory impairment derives from the inefficient orchestration of rhythmic activity at the level of large-scale cortical networks. The results as expected to elucidate AD-related pathophysiology and set groundwork for the development of drug-free interventions for improving memory in AD and related dementias.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • High definition transcranial electrical current stimulation

    Device

    Low-intensity and safe, noninvasive application of electrical current to the human scalp with the goal of gradually modulating levels of neuronal excitability.

Treatment groups

204 Participants
are divided into 2 treatment groups
Group A: active stimulationExperimental treatment 1 intervention
Group B: sham stimulationSham comparator 1 intervention

Trial outcomes

Primary outcomes

1

Memory performance (active stimulation condition)

The accuracy of task performance on memory test

Time frame
Time Frame: Memory performance data is collected during active brain stimulation and reported 1 year later
2

Memory performance (sham stimulation condition)

The accuracy of task performance on memory test

Time frame
Time Frame: Memory performance data is collected during sham brain stimulation and reported 1 year later

Secondary outcomes

Other outcomes

Sponsors and contacts

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