Improving Real-world Function for Persons with Schizophrenia: a Single-case Experimental Design

ConditionSchizophrenia
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-59
SponsorSykehuset Innlandet HF

About this trial

Existing treatment for individuals with psychosis primarily targets positive symptoms but has only modest effects on cognition and negative symptoms. Cognitive strategy training shows promising effects in reducing negative symptoms and increasing activity initiation in individuals with schizophrenia.

This project aims to investigate the effect of the Perceive, Recall, Plan and Perform (PRPP) intervention in promoting effective use of cognitive strategies for adults with schizophrenia in performing their daily activities. Twenty-seven individuals with schizophrenia will be recruited from Sykehuset Innlandet (Innlandet Hospital Trust) and assessed using PRPP prior to an eight-session PRPP intervention. Re-assessment will be conducted after the intervention, as well as at 3 and 6 months, to evaluate the long-term effects of the intervention. A single-case design will be used to investigate the intervention's effects. The primary outcome measure will be the PRPP assessment, and the secondary outcome measure will be the Goal Attainment Scale (GAS). Generalization measures will be used to evaluate whether there are relevant changes beyond the primary and secondary goals.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

DSM-5 diagnosis of schizophrenia, understand and speak Norwegian, live in their own community context, but are patients in Sykehuset Innlandet ( Innlandet Hospital Trust), either as outpatients or on discharge from inpatient care, a subjective experience of functional impairment and/or cognitive difficulties identified in an initial interview, and a stable state without any major medication change for at least two months before inclusion

Disqualifiers

Major physical disability, a current substance abuse problem, and cognitive deficits of organic origin or mental retardation

Trial design

Design model

Single group

Treatments tested in this trial

  • Perceive, Recall, Plan and Perform intervention Interventions:

    Behavioral

    The PRPP is a standardized system which determines the impact of information processing on performance of everyday activities. It is a method for assessment of performance mastery, and efficient use of cognitive strategies, as well as a model of intervention to train mastery and cognitive strategy use, in everyday activities. The PRPP assess task performance mastery, as well as cognitive strategy application

Treatment groups

27 Participants
are divided into 1 treatment group
Group A: Perceive, Recall, Plan and Perform interventionOther 1 intervention

Trial outcomes

Primary outcomes

1

PRPP assessment

Effective use of cognitive strategies in performing their daily activities

Time frame
Assesments just after the intervention, as well as at 3 and 6 months

Secondary outcomes

1

Goal Attainment Scale

Time frame
Assesments just after the intervention, as well as at 3 and 6 months
2

Health of the Nation Outcome Scale

Time frame
Assesments just after the intervention, as well as at 3 and 6 months
3

Social Functioning Scale

Time frame
Assesments just after the intervention, as well as at 3 and 6 months
4

Questionnaire about the Process of Recovery

Time frame
Assesments just after the intervention, as well as at 3 and 6 months

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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Sykehuset Innlandet HF

Lead sponsor

Norwegian University of Science and Technology

Collaborator

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