Inbon Errors of Immunity Attending Assiut University Children&Amp;#39;s Hospital: a Single Center Study

ConditionPrimary Immunodeficiency Diseases (PID)

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

AgeUp to 18

SponsorAssiut University

About this trial

Aim of Study The aim of this study to describe the clinical profile of children diagnosed as IEIs who were admitted to in Assiut university children\&#39;s Hospital.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

patients without any criteria of ten warning signs

Trial population

Sex- all Age - maximum age 18 y

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

Inborn errors of immunity
Diagnostic test
A. Routine .1CBC with blood film. .2Liver Function Test. .3Kidney Function Test. 4\. Inflamatory marker ESR, CRP B.Immunology 1. Immunoglobulins IgG, IgM, IgA, IgE 2. Flow cytometric assessment: B Cell (CD19), T cells (CD3,CD4, CD8) anc NK Cells (CD16+56) and other markers whenever needed (e.g. CD40, CD40L for cases of hyper IGM) 3. Chest x-ray to assess thymus and any abnormality 4. DHR123 whenever needed (e.g. chronic granulomatous disease). 5. LAD panel (CD11b CD15-CD18) whenever needed. 6\. Complement assay (CH
A. Routine .1CBC with blood film. .2Liver Function Test. .3Kidney Function Test. 4. Inflamatory marker ESR, CRP B.Immunology 1-Immunoglobulins IgG, IgM, IgA, IgE 2-Flow cytometric assessment: B
Diagnostic test
A. Routine .1CBC with blood film. .2Liver Function Test. .3Kidney Function Test. 4\. Inflamatory marker ESR, CRP B.Immunology 1. Immunoglobulins IgG, IgM, IgA, IgE 2. Flow cytometric assessment: B Cell (CD19), T cells (CD3,CD4, CD8) anc NK Cells (CD16+56) and other markers whenever needed (e.g. CD40, CD40L for cases of hyper IGM) 3. Chest x-ray to assess thymus and any abnormality 4. DHR123 whenever needed (e.g. chronic granulomatous disease). 5. LAD panel (CD11b CD15-CD18) whenever needed. 6\. Complement assay (CH

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

Profile of Patients with Inborn Errors of Immunity in Assiut University Children Hospital: Single Center Study

Warning signs for early diagnosis * Weight in kilogram * Height in meters investigation --Routine * CBC with blood film. * Liver Function Test. * Kidney Function Test. * Inflammatory marker ESR,CRP --Immunology * Immunoglobulins IgG, IgM, IgA, IgE * Flow cytometric assessment: B Cell (CD19), T cells (CD3,CD4, CD8) and NK Cells (CD16+56) and other markers whenever needed (e.g. CD40, CD40L for cases of hyper IGM) * Chest x-ray to assess thymus and any abnormality * DHR123 whenever needed (e.g. chronic granulomatous disease). * LAD panel ( CD11b CD15- CD18) whenever needed. .Complement assay (CH 50,C3,C4) whenever needed .

Time frame

Baseline

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

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