Incidence of Slow Delta EEG Frequencies (0.1-1 Hz) Before Burst Suppression
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age60+
SponsorInsel Gruppe AG, University Hospital Bern
About this trial
The electroencephalogram (EEG) measures brain waves during general anaesthesia via an electrode placed on the forehead. These brain waves show the different stages of natural sleep as well as the state of the brain when a patient is put under general anaesthesia for an operation. In this research project, the investigators aim to find out if the EEG signal shows slow wave activity (where an EEG wave repeats every 10 to 1 seconds) just before the onset of the burst suppression pattern, where the EEG waveform alternates between very small (suppression) and very large (burst) signals over a period of a few seconds. It is not currently known if and how often this occurs, but if it does, it would be a useful signal to help anaesthetists administer just the right dose of anaesthesia to patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
patients undergoing elective general anaesthesia, and
aged 60 or above, and
have a good comprehension of German, and
require a general anaesthesia length of at least 1 hour (to ensure that we can record enough good quality EEG signal).
Disqualifiers
patients undergoing head or neck surgery or surgery in prone or lateral decubitus position (due to the limited placement space on the forehead required for the two EEG electrode systems, limited access to the forehead during surgery), or
patients undergoing emergency surgery, operations only requiring local or regional anaesthesia with sedation, or
patients who cannot follow procedures, or have an inability to give consent, or
known participation in another human research project (ClinO/HRO) that may affect the objectives of this study.
Trial population
Patients requiring elective surgery at either the Cantonal Hospital of Aarau, Switzerland, or at the Hirslanden Clinic Aarau, Switzerland.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
30 Participants
are grouped into 1 trial groupGroup A: Patients over 60 requiring general anesthesia
Trial outcomes
Primary outcomes
1
Slowwave Peak Amplitudes prior to Burst Suppression
The primary variables of interest are peak amplitudes in the slow wave signal and absolute power in the EEG frequency spectra when recorded from immediately prior to the onset of burst suppression.
Time frame
This outcome is measured during the anesthesia for surgery, i.e., between when a patient is anaesthetised until they wake up following the operation, all on the same day.Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Insel Gruppe AG, University Hospital Bern
Lead sponsor
Kantonsspital Aarau
Collaborator
Hirslanden Clinic Aarau
Collaborator
Source ClinicalTrials.gov
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