Individual Narratives of Stimulation (ECT and TMS)

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Nottingham

About this trial

Electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) are two evidence-based treatments for major depressive disorder. Both work by stimulating the brain (a process known as neuromodulation), but they differ markedly in invasiveness. ECT requires a general anaesthetic, whereas TMS is delivered while a person is awake and alert and they can go home immediately afterwards. TMS has been proposed as an alternative to ECT for some people. However, TMS is not as effective as ECT in all cases, is generally slower acting, and remains less widely available.

In Nottingham and Liverpool, there are a small number of individuals who have experienced both ECT and TMS across different episodes of depression. Whilst previous studies have explored experiences of ECT and TMS separately, often using relatively superficial methods, none have examined the perspectives of people who have received both treatments. This study addresses that gap through an in-depth exploration of their experiences.

The investigators will use a narrative inquiry approach that encourages participants to tell the story of their experiences of ECT and TMS in their own words. Eligible participants will be adults who have previously received both treatments for depression. Participation involves four sessions: a structured discussion to map the timeline of their depression and treatments, two in-depth open-ended interview sessions (narrative inquiry), and a follow-up discussion about the researchers' reconstruction of their story. Recruitment will take place through services in Nottingham and Liverpool.

This study will help to understand how patients relate to, and make sense of, ECT and TMS, which contextual factors shape their experiences, and how these treatments fit into broader recovery journeys. The findings will inform the development of patient-centred services, support shared decision-making, and help healthcare professionals deepen compassionate understanding of treatment experiences.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

18 years or older

Previously received at least one TMS and one ECT session as treatment for major depression

Conversational in the English language

Capacity to give informed consent to take part in this study

Disqualifiers

Participants may be excluded at the judgement of the PI if it is felt that the participant is at high risk of significant emotional distress from taking part in the interviews at this time

Trial population

Adults who have received at least one session of TMS in Nottingham or Liverpool, who have also received at least one session of ECT, both intended to treat an episode of major depression

Trial design

Design model

Case-only

Time perspective

Prospective

Treatments tested in this trial

  • There is no intervention in this observation study (qualitative interviews about past treatment experiences)

    Other intervention

    There is no intervention in this observation study (qualitative interviews about past treatment experiences)

Treatment groups

12 Participants
are divided into 1 treatment group
Group A: People with lived experience of both ECT and TMS for treating major depression1 intervention

Trial outcomes

Primary outcomes

1

Co-created narratives and associated themes

Time frame
From enrollment to the completion of the follow-up feedback sesson

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Nottingham

Lead sponsor

Mersey Care NHS Trust

Collaborator

This trial is not recruiting at the moment. You can still explore other options: