Individualized vs Standard PEEP and Oxygen Reserve Index in Laparoscopic Hernia Surgery

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorFatih Sultan Mehmet Training and Research Hospital

About this trial

During laparoscopic surgery under general anesthesia, lung function can be affected by increased abdominal pressure and patient positioning. Positive end-expiratory pressure (PEEP) is a ventilator setting that helps keep the lungs open during surgery. In standard practice, a fixed PEEP level is applied to all patients. An individualized PEEP approach tailors this setting to each patient based on lung recruitment maneuvers.

This study investigates whether individualized PEEP improves oxygenation compared to standard PEEP in patients undergoing laparoscopic inguinal hernia surgery. Oxygenation will be continuously monitored using the Oxygen Reserve Index (ORI), a non-invasive sensor. Lung aeration will also be assessed before and after surgery using bedside lung ultrasound.

Eligibility criteria

Qualifiers

Aged 18-75 years

ASA physical status I-III

Scheduled for elective laparoscopic unilateral inguinal hernia repair under general anesthesia

Body mass index (BMI) < 35 kg/m²

Disqualifiers

Age below 18 or above 75 years

ASA physical status IV-V

Emergency surgical procedure

Severe chronic or restrictive pulmonary disease

Trial design

Treatments tested in this trial

  • Standard PEEP Ventilation
  • Individualized PEEP Ventilation

Treatment groups

60 Participants
are divided into 2 treatment groups