Patients undergoing cystectomy for either oncological or non-oncological indications are prospectively enrolled following informed consent. This study design incorporates a comprehensive medical history, detailed prospective documentation of clinicopathological parameters, and serial measurements of infectious markers pre- and post-operatively. In-hospital complications are meticulously recorded, and long-term outcomes assessed through structured follow-up interviews at 3, 6, and 12 months. These follow-ups utilize standardized questionnaires to evaluate post-discharge infectious complications and gather patients' perspectives on their in-hospital experiences, providing a robust understanding of both clinical outcomes and patient-reported experiences.
Disease which requires removal of the urinary bladder
Patient does not want to participate
Patients who undergo cystectomy
Cohort
Prospective
Cystectomy
Procedure/SurgeryRemoval of the urinary bladder
Infectious parameters on the first postoperative day after cystectomy
IL-6 level, procalcitonin level and wound drainage culture
Postoperative fever
Proportion of cystectomy patients that develops fever postoperatively (≥38.0°C)
Antibiotic use
Proportion of cystectomy patients that need additional oral or i.v. antibiotic therapy (on top of the hospital standard)
In-hospital complications
Clavien-Dindo Classification and Comprehensive Complication Index
IMCU/ICU nights
Number of nights spent at a IMCU/ICU postoperatively
Duration of hospital stay
Total hospital stay (nights)
Subjective grading of in-hospital complications
Subjective assessment: no complications, minor complications or major complications
Rating of the pre-operatively provided medical information
Subjective assessment: very good, good, satisfactory, sufficient, not sufficient
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