Prospective observational study designed to describe the clinical, laboratory, imaging, microbiological characteristics and treatment of specific infectious diseases, with the addition of a dedicated biobank.
Patients with clinically suspected or microbiologically documented infectious diseases (bacterial, viral, fungal or parasitic);
At least 18 years of age or older;
Able to provide informed consent;
Participants who are unable to understand the study protocol or are unable to give informed consent, but have a legal representative
None
Patients with specific infectious diseases followed at the IRCCS San Raffaele Hospital (either as inpatients or outpatients).
Cohort
Prospective
Not listed
Clinical characteristics of specific infectious diseases
Describe the clinical presentation of specific infectious diseases, by means of Sequential Organ Failure Assessment (SOFA) score (minimum 0 - maximum 24; higher scores linked to worse outcome).
Microbiological characteristics of specific infectious diseases
Describe the microbiological characteristics of specific infectious diseases. Specifically: * Identification of the causative organisms * Antimicrobial susceptibility testing results * Mechanism of resistance
Treatment of specific infectious diseases
Describe the antimicrobial treatment of specific infectious diseases
Predictive factors of microbiological cure
Describe the predictive factors of microbiological cure, defined as negativization of cultures from the infected site
Predictive factors of clinical cure
Describe the predictive factors of clinical cure, defined as resolution of symptoms and signs attributable to the specific infectious disease
Need for surgical intervention or other procedures
Describe the number of patients needing surgical intervention or other procedures
Need for ICU
Describe the number of patients needing ICU transfer
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IRCCS San Raffaele
Lead sponsor
Ospedale San Raffaele
Sponsor institution
