This pilot randomized clinical trial aims to evaluate the effect of adjunctive acid application on the esthetic outcomes of gingival melanin depigmentation. Participants with physiologic gingival hyperpigmentation will be randomly assigned to receive conventional gingival depigmentation with or without adjunctive acid application. The primary outcome is the improvement in gingival esthetics, while secondary outcomes include postoperative healing, pain, patient satisfaction, and recurrence of pigmentation. The findings of this study may help identify whether adjunctive acid application improves the clinical outcomes of gingival depigmentation procedures.
Adults aged 18-50 years.
Presence of physiologic gingival melanin pigmentation requiring treatment.
Good general health.
Good periodontal health or a healthy periodontium after initial periodontal therapy.
Current smokers or tobacco users.
Pregnancy or breastfeeding.
History of systemic diseases that may affect wound healing (e.g., uncontrolled diabetes or immunocompromised conditions).
Use of medications known to affect gingival pigmentation or wound healing.
Parallel
Citric acid
DrugAdjunctive topical application of citric acid during gingival melanin depigmentation according to the study protocol to evaluate its effect on esthetic outcomes and healing.
Esthetic Outcome of Gingival Melanin Depigmentation
Assessment of the esthetic improvement following gingival melanin depigmentation with or without adjunctive acid application using the study's predefined esthetic evaluation method.
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