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Influence of Iyengar Yoga on the Bio-functional Age of Postmenopausal Women

ConditionsPostmenopausalPostmenopausal Flushing
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorInsel Gruppe AG, University Hospital Bern

About this trial

The purpose of this Study is to find out if Iyengar-Yoga has a rejuvenating effect on women after menopause. The biofunctional status of the study participants will be assessed before and after a 12-week yoga program.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Informed consent

Women after Menopause (defined as 12 months of spontaneous amenorrhea or 6 months of spontaneous amenorrhea with serum FSH levels >40mlU/ml or 6 weeks postsurgical bilateral oophorectomy with or without hysterectomy)

Age over 18 years

At least 4 hot flushes per day (examined through the Menopause rating scale MRS-II)

Disqualifiers

Acute and/or serious disease in the past two years (e.g. Cancer, major surgery)

Autoimmune or chronic inflammatory disease (e.g. rheumatism, thyroid dysfunction)

Mental illness (e.g. Depression or anxiety disorder (HADS >8))

Acute or chronic back pain or herniated vertebral disc

Trial design

Design model

Parallel

Treatments tested in this trial

  • Iyengar Yoga

    Behavioral

    Weekly 90 minute Iyengar Yoga classes taught y a professional instructor. Twice weekly 45 minute self practice of Iyengar Yoga at home by the participants

Treatment groups

72 Participants
are divided into 2 treatment groups
Group A: InterventionExperimental treatment 1 intervention
Group B: ControlNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Decrease of the biofunctional age (BFA) through a 12 week Iyengar yoga intervention compared to the control group with no yoga classes. In order to evaluate the BFA a biofunctional Status (BFS) has to be assessed.

The BFS is a generic, age- and sex-specific test battery comprising holistic characteristics from physical, mental-emotional and social areas. The single values of the BFS test battery were scaled and differentiated for chronological age (CA) and sex. Their summation makes up the so-called Bio-functional Age Index BFAI (BFAI = Σ (B-X/B-L)n/n). The BFAI is a relative measure compared to a reference population, out of which norm charts were developed. By definition, the reference population's BFAI is identical with its CA. A BFAI of an individual may be transformed into BFA (years) by means of gerontologic aging tables. This BFA (years) relates to the mean value of a certain CA. The BFA is based on a sex-specific regression and factor analysis of functional age (Mathieu et al., 2018. Illness perception in overweight and obesity and impact on bio-functional age. Archives of gynecology and obstetrics, 298(2), p. 417)

Time frame
12 weeks

Secondary outcomes

1

Hot flushes

Change of the climacteric symptom hot flushes (number per day) measured at the beginning and after 12 weeks of the intervention

Time frame
12 weeks
2

Level of High sensitive C-reactive protein (HS-CRP)

Change of the climacteric symptom Level of HS-CRP (mg/l) measured at the beginning and after 12 weeks of the intervention

Time frame
12 weeks
3

Oxidative balance

Change of the climacteric symptom oxidative balance measured at the beginning and after 12 weeks of the intervention

Time frame
12 weeks

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Insel Gruppe AG, University Hospital Bern

Lead sponsor

Source ClinicalTrials.gov
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