About this trial
The purpose of this study is to help understand how attention processes influence brain engagement during emotion and social cognition. The investigators also want to know if these processes are associated with drinking alcohol.
Participation includes three study visits of about 2 hours each over approximately a month. The first visit involves a magnetic resonance imaging (MRI) scan and answering survey questions. Each of the next two visits will involve a session of transcranial magnetic stimulation (TMS, a non-invasive brain stimulation technique) followed by another MRI scan.
People in the Auburn/Opelika area 19 or older are eligible to participate. People who drink alcohol and people who do not drink or don't drink very much are invited to participate.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
MRI Contraindications
Presence of metal in the body that would make having a 7T MRI unsafe (including facial tattoos)
Claustrophobia, such that individual would be unable to stay in the MRI for up to 1 hr
Hearing loss, including tinnitus, that might be made worse by MRI or TMS
Trial design
Crossover
Treatments tested in this trial
TMS
DeviceTMS will be administered in a pattern that is either excitatory or inhibitory.
Treatment groups
Trial outcomes
Primary outcomes
Change in attention switching
MRI Task- analysis of behavioral data
Change in sociomoral attention switching
MRI Task- analysis of behavioral data
Change in cue reactivity
MRI Task- analysis of behavioral data
Secondary outcomes
Change in brain activity attention switching
MRI Task- analysis of imaging (fMRI) data
Change in brain activity during sociomoral attention switching
MRI Task- analysis of imaging (fMRI) data
Change in brain activity during cue reactivity
MRI Task- analysis of imaging (fMRI) data
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Auburn University
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Collaborator