Inhibitory Control and Gait Adaptability in Parkinson's Disease
ConditionParkinson Disease (PD)
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorNational Yang Ming Chiao Tung University
About this trial
People with Parkinson's disease (PD) may have difficulty stopping or changing their movements, especially when walking around obstacles.
The goal of this observational study is to learn if a specific cognitive function, called inhibitory control (the ability to stop or control actions) is associated with gait adaptability in people with Parkinson's disease. Gait adaptability means the ability to adjust how a person walks in response to changes in the environment, such as stepping over obstacles.
The main questions the study aims to answer are:
* If brain activation related to inhibitory control, measured by EEG, is associated with gait adaptability during obstacle crossing in people with Parkinson's disease? * If behavioral inhibitory control is associated with gait adaptability during obstacle crossing in people with Parkinson's disease?
Participants take part in one study visit. During this visit, participants complete simple thinking tests, have their brain activity recorded using EEG, and perform walking tasks that include stepping over obstacles.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
A clinical diagnosis of idiopathic Parkinson's disease;
Stable use of prescribed antiparkinsonian medication for at least two weeks;
Modified Hoehn and Yahr stage I to III;
Age between 18 and 80 years;
Disqualifiers
The presence of any neurological, musculoskeletal, or cardiovascular disorders that could affect participation in this study;
The presence of psychiatric disorders that could interfere with the ability to follow instructions or comply with study procedures;
A history of brain surgery, such as deep brain stimulation (DBS)
Trial population
Community
Trial design
Design model
Case-only
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Event-related potential - N2
Measure event-related potential through electroencephalography during the Go/No-go test
Time frame
1 day2
Event-related potential - P300
Measure event-related potential through electroencephalography during the Go/No-go test
Time frame
1 day3
Stroop color and word test
Record numbers of corrected color words which the subject responds within 45 sec
Time frame
1 day4
Step width
Using the GAITRite system to measure step width
Time frame
1 daySponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: