Innate Immune Cell Phenotypes and Early Fibrotic Repair in Acute Myocardial Infarction

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorShanghai 10th People's Hospital

About this trial

To determine the relationship of the phenotypes of neutrophils and monocytes with early fibrotic repair after acute myocardial infarction.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Prior revascularization

Known allergy to gadopentetate dimeglumine contrast agent

Pregnancy or planned pregnancy within the next 6 months

Life expectancy < 1 year

Trial population

STEMI patients undergoing PPCI

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

50 Participants
are grouped into 1 trial group
Group A: STEMI patients

Trial outcomes

Primary outcomes

1

Major cardiac adverse outcome

The composite endpoint included cardiac death, non-fatal myocardial infarction, and rehospitalization for angina.

Time frame
At 12 months after enrollment

Secondary outcomes

1

Cardiac remodeling measured by CMR

CMR will be performed to evaluate the cardiac fibrosis defined as area of late gadolinium enhancement (LGE).

Time frame
At 1 week after admission

Other outcomes

Sponsors and contacts

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