Innovative 3D Preclinical Models for Mature B-cell Malignancies to Advance Personalized Immuno and Combination Therapies
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIRCCS San Raffaele
About this trial
Adult patients with chronic lymphocytic leukemia (CLL), splenic marginal-zone lymphoma (SMZL) and hairy cell leukemia (HCL) followed at participating clinical sites will be enrolled and undergo sampling of additional amount of blood during the blood draws performed as part of standard clinical care.
The project aims to develop and validate innovative patient-derived 3D bioprinted models that faithfully reproduce the key microenvironments of lymphoid tissues, enabling a more physiologically relevant study of mature B-cell malignancies.
Eligibility criteria
Qualifiers
Age ≥18 years
Diagnosis of CLL, SMZL or HCL
Participant is willing and able to autonomously give informed consent for participation in the study.
Disqualifiers
None
Trial design
Treatments tested in this trial
- Not listed
Trial groups
64 Participants
are grouped into 3 trial groupsSponsors and collaborators
IRCCS San Raffaele
Lead sponsor
Ministry of Health, Italy
Collaborator
Source ClinicalTrials.gov