Inorganic Pyrophosphate Homeostasis (PPi) in Pediatric Chronic Kidney Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age0-18
SponsorCentre Hospitalier Universitaire de Nice

About this trial

The investigator aim to identify the role of inorganic pyrophosphate and other anti-calcifying molecules in vascular disease in children with chronic kidney disease, with a view to developing therapeutic approaches aimed at limiting the onset of vasculopathy.

Eligibility criteria

Qualifiers

Minor patients (<18 years)

Patients of both sexes

Informed patients and parents who have signed the informed consent form

Patients affiliated to social security

Disqualifiers

Progressive cancer or kidney disease

Treatments that may modify PPi concentration (e.g. bisphosphonates)

Trial design

Treatments tested in this trial

  • PPI and T50 dosing

Treatment groups

60 Participants
are divided into 4 treatment groups