About this trial
Existing data points to relevant beneficial effects of respiratory exercises on cardiovascular health, with special regards to decreases on arterial pressure and improves on autonomic and vascular profiles, though mechanistics of such results have not yet been cleared. Among the available ways to perform respiratory exercises, there is the highly recommended Inspiratory Muscle Training (IMT) and slow breathing exercises like Yoga pranayamas. Lately, the development of new technologies has allowed the use of Apps to perform respiratory exercises. This study will be take the just developed CardioBreath®App to validate it as a tool to perform respiratory exercises. Therefore, it will be compared to IMT on cardiac vagal modulation and pulse wave velocity on normotensive post menopause women.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Follicle Stimulating Hormone (FSH)>35mui/ml
minimum 12 months amenorrhea
sedentary life style (less than 150 minutes per week of exercise)
Disqualifiers
Hypertension
Diabetes
Obesity
Use of Betablockers
Trial design
Sequential
Treatments tested in this trial
CardioBreathApp
DeviceRespiratory exercises performed with CardioBreathApp prescription and voice and visual guidance
IMT PowerBreath
DeviceInspiratory Muscle Training (IMT) performed with 30% load based on Maximal Inspiratory Pressure
IMT PowerBreath Placebo
DeviceInspiratory Muscle Training (IMT) without load
Treatment groups
Trial outcomes
Primary outcomes
Cardiovascular autonomic control by heart rate variability(HRV)
High Frequency (HF) component of HRV (ms2 = squared milliseconds) as measure of vagal modulation
Secondary outcomes
Carotid -femoral pulse wave velocity (Complior)
Reduction of carotid -femoral pulse wave velocity (m/s)
Other outcomes
Respiratory rate by Pneumotrace respiratory belt
Respiratory rate in cycles per minute (CPM)
Diaphragm Thickness by ultrasound
Increase diaphragm thickness (mm)
Sponsors and contacts
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