About this trial
The goal of this observational study is to evaluate the implementation of the INSPIRE program and to plan actions for the preparation, coordination, monitoring, diagnosis, and treatment of respiratory diseases in the municipality of Botucatu. Methods: Individuals with respiratory symptoms from the municipality of Botucatu, aged 18 or older, will be invited to participate in the study, and socioeconomic data, as well as information on sex, gender, race, nutritional risk, frailty, tobacco exposure, and its derivatives, will be collected. For those with exposure, screening and treatment for respiratory diseases will be offered through assessment of pulmonary function, body composition, respiratory and peripheral muscle strength. Additionally, individuals over 40 years old with tobacco exposure equal to or greater than 30 pack-years will be offered low-dose chest CT screening for lung cancer. Expected results: To identify and assess vulnerable groups that face difficulties in accessing respiratory healthcare, as well as implement specific strategies for the treatment of respiratory diseases and tobacco control for these groups. To ensure equitable access to respiratory health for the entire population at risk due to smoking. Moreover, through proactive and reactive risk reduction actions implemented by the program, to intervene in distinct groups and other regions.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age equal to or greater than 18 years old;
Respiratory symptoms
History of active or passive smoking
Signing of informed consent form
Disqualifiers
Difficulty understanding the issues addressed
Inability to contact by phone
Non-signing or withdrawal of informed consent
Trial population
Individuals with a history of smoking and/or passive exposure and/or respiratory symptoms residing in the city of Botucatu, state of São Paulo, Brazil.
Trial design
Cohort
Prospective
Treatments tested in this trial
Analysis of results
Other interventionAnalysis of previous imaging and/or laboratory tests, vital signs, body composition, pulmonary function, peripheral muscle strength, calf circumference, nutritional risk, quality of life, frailty level, and anxiety and depression. Screening for respiratory diseases, including chronic obstructive pulmonary disease (COPD), lung cancer, tuberculosis, and other lung lesions, is based on spirometry and thoracic radiological images after the health professional's examination. After the multiprofessional procedures, patients will be evaluated by a physician to start specific treatment and/or perform complementary exams if necessary. Every year, they will be re-evaluated to record acute exacerbations of chronic respiratory diseases and assess disease progression through spirometry and thoracic radiological images.
Treatment groups
Trial outcomes
Primary outcomes
Evaluation of changes in respiratory disease incidence following the implementation of the INSPIRE Program in Botucatu
This primary outcome assesses the program's effectiveness in public health by directly measuring changes in the incidence of respiratory diseases within the target population
Secondary outcomes
Program implementation costs
This measure estimates the total costs associated with implementing the program. It includes all expenditures related to program activities and administration.
Sponsors and contacts
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UPECLIN HC FM Botucatu Unesp
Lead sponsor
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Collaborator