Integrated Rehabilitation in HDU for Post-Intensive Care SyndromeLiberation in Patients With PICS

ConditionsPost-Intensive Care Syndrome (PICS)Critical Illness Recovery Mechanical Ventilation

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorHongying Jiang, MD

About this trial

Post-intensive care syndrome (PICS) is characterized by persistent physical, cognitive, and psychological impairments among survivors of critical illness. Although advances in intensive care medicine have reduced mortality, a large proportion of ICU survivors experience long-term functional impairments after discharge.

High-dependency units (HDUs) serve as transitional care settings between intensive care units and general wards. Many critically ill survivors who cannot directly return home are transferred to HDU for continued treatment and rehabilitation. However, evidence regarding systematic multidisciplinary rehabilitation interventions in HDU settings remains limited.

This prospective single-center interventional study aims to evaluate the effects of an integrated multidisciplinary rehabilitation model implemented in the HDU on physical, cognitive, and psychological outcomes among patients with post-intensive care syndrome. All enrolled patients will receive standardized integrated medical, nursing, and rehabilitation interventions. Multidimensional functional assessments will be conducted at baseline, during hospitalization, and before discharge from the HDU.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age ≥18 years

Diagnosed with post-intensive care syndrome

Transferred from ICU to HDU

Available paired admission and discharge data

Disqualifiers

Death within 24 hours after HDU admission

Missing primary outcome data

Trial design

Design model

Single group

Treatments tested in this trial

Integrated Multidisciplinary Rehabilitation
Behavioral
Participants will receive a standardized multidisciplinary rehabilitation program implemented in the HDU, including: Medical management Continuous treatment of primary diseases, medication optimization, complication prevention, and gradual removal of medical devices. Respiratory rehabilitation Respiratory muscle training, airway clearance techniques, and breathing pattern training. Physical rehabilitation Progressive mobilization according to patient tolerance, including passive exercises, active bed exercises, sitting training, standing training, and walking training. Sessions are conducted 1-2 times per day, lasting 20-40 minutes each. Rehabilitation nursing Position management, pressure injury prevention, device safety management, and sleep management. Cognitive and psychological interventions Orientation training, cognitive stimulation activities, psychological support, and family participation.

Treatment groups

250 Participants

are divided into 1 treatment group

Group A: Integrated Multidisciplinary Rehabilitation in HDUExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Change in Physical Function (CPAx Score)

Change in Chelsea Critical Care Physical Assessment Tool (CPAx) score from baseline to HDU discharge. The CPAx score ranges from 0 to 50, with higher scores indicating better physical function.

Time frame

Baseline (within 48 hours after HDU admission) and at HDU discharge，assessed up to 2 days

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Hongying Jiang, MD

Lead sponsor

Capital Medical University

Sponsor institution

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: