Intelligent Analysis and Clinical Validation of Cerebral Small Vessel Disease on Magnetic Resonance Imaging:A Multi-center Study

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40+
SponsorChinese PLA General Hospital

About this trial

Cerebral small vessel disease (CSVD) accounts for 20% of ischemic strokes and is the most common cause of vascular cognitive impairment. Early identification of CSVD is critical for early intervention and improve clinical outcomes. Magnetic resonance imaging (MRI) may represent as a sensitive and robust tool to detect early changes in brain subtle structures and functions. The study is to investigate the comprehensive evaluation by using AI in early diagnosis and management of CSVD.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

① Men and women age 40 years or older;

At least one vascular risk factor has been identified, including hypertension, diabetes, hyperlipidemia, coronary heart disease, and chronic kidney disease;

The patient performed two brain MRI Examinations simultaneously at a time interval of more than 6 months (≥6).

Disqualifiers

① The patient had no vascular risk factors;

No clinical follow-up images;

There are significant motion artifacts in the image, which cannot meet the

Trial population

This is a multicenter study with a total plan of 1000 patients, 500 from Chinese PLA General Hospital and 500 from other centers.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Artificial intelligence

    Diagnostic test

    Artificial intelligence (AI) tools developed through the training of large amounts of image data can assist with the analysis and interpretation of neuroimaging data of cerebral small vascular disease(CSVD).

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

The performance of AI in lesion detection and diagnosis

The performance of AI in lesion detection and diagnosis, including imaging quality, accuracy, sensitivity and specificity in lesion detection and imaging diagnosis.

Time frame
2 year

Secondary outcomes

Other outcomes

Sponsors and contacts

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