About this trial
The objective of this study is to determine if early parametric positron emission computed tomography is useful to diagnose cardiac prosthetic valve infections.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age superior to18 years,
Effective contraception for women of childbearing age or negative pregnancy test on the day of the exam
Good general condition. WHO ≤ 1
Suspicion of endocarditis on a prosthetic heart valve implanted more than 3 months ago
Disqualifiers
Presence of an active cancer in the previous three years
Pregnancy or breastfeeding
Poorly controlled diabetic patients
Protected adults (under guardians or curators)
Trial design
Single group
Treatments tested in this trial
Parametric positron emission computed tomography
DevicePatients will undergo parametric positron emission computed tomography in 15 days after the labeled polynuclear scintigraphy
Treatment groups
Trial outcomes
Primary outcomes
Determination of diagnostic value of parametric positron emission computed tomography
area under the curve of the Ki parameter (and the Vd parameter) as a function of the presence of endocarditis diagnosed during the multidisciplinary consultation meeting at 3 months
Secondary outcomes
Correlation between parametric positron emission computed tomography and scintigraphy with labelled leukocytes
comparison between diagnosis established by parametric positron emission computed tomography and scintigraphy with labelled leukocytes
Sponsors and contacts
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