About this trial
Evaluate the patient care recommandation induced by the IMMUNOSCORE® result
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
age between 18 and 80 inclusive;
histologically confirmed colon adenocarcinoma;
having undergone a curative resection of stage I, II or III colorectal cancer;
diagnosed T1 / T2 / T3 / T4 and N0 / N1 / N2;
Disqualifiers
pregnant or breastfeeding women
legal incapacity or physical, psychological, social or geographical conditions preventing the patient from signing the consent or completing the study.
history of other solid tumor within 3 years before inclusion, with the exception of in-situ cancer of the cervix and skin cancers (basal or squamous) treated and controlled
person subject to a safeguard measure.
Trial design
Single group
Treatments tested in this trial
IMMUNOSCORE®
Diagnostic testrecommendation for patient care according to the result of the IMMUNOSCORE®
Treatment groups
Trial outcomes
Primary outcomes
Number of cases where the recommendations for patient care according to the Immunoscore® are considered beneficial compared to the standard care decision
Secondary outcomes
Replication error (RER) phenotype
Number of cases where the Immunoscore® resultat is inconsistent with the RER phenotype
KRAS, NRAS and BRAF mutations
Number of cases where the Immunoscore® resultat is inconsistent with the KRAS, NRAS and BRAF mutations
Ratio of ciruclating tumor DNA level
Number of cases where the Immunoscore® resultat is inconsistent with the ratio of ciruclating tumor DNA level
Actual survival (patient alive without recurrence, alive with recurrence, dead)
Number of cases where the Immunoscore® resultat is inconsistent with the actual survival
Sponsors and contacts
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