International Severe Asthma Registry: Canadian Cohort

ConditionSevere Asthma
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of British Columbia

About this trial

The International Severe Asthma Registry is a global initiative looking to ensure that the care of people with severe asthma will continue to improve by collecting detailed information about the health and treatment of as many people with the disease as possible. The study will gather anonymized longitudinal real-life data for participants with severe asthma for five years. The purpose of the registry is to track the progress of participants and determine how well they are responding to treatment. Medical research using data from the registry will give the investigators a better understanding of severe asthma and help the investigators develop and improve the care and treatment for severe asthma participants. The Canadian cohort of the registry will collect information from Canadian participants with severe asthma across seven different sites.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Participants 18 years or older

Participants receiving treatment according to GINA Step 5 or uncontrolled in GINA Step 4 (uncontrolled is defined as having severe asthma symptoms or frequent exacerbations)

Disqualifiers

None

Trial population

The study population will be selected from respirology/pulmonary clinics across Canada. Participants will be identified and recruited by the study investigators and study staff based on their clinical presentation.

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

714 Participants
are grouped into 1 trial group
Group A: Severe Asthma Participants

Trial outcomes

Primary outcomes

1

Blood eosinophil counts

10\^9/L

Time frame
Past 12 months
2

Blood Immunoglobulin E (IgE) counts

kilo unit/L

Time frame
Past 12 months
3

Fractional exhaled nitric oxide level

parts per billion

Time frame
Past 12 months
4

Start and end dates of oral corticosteroid medication

Day/Month/Year for start and end dates if available

Time frame
Prior to baseline visit

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of British Columbia

Lead sponsor

University of Alberta

Collaborator

University of Toronto

Collaborator

Laval University

Collaborator

McGill University

Collaborator

Université de Sherbrooke

Collaborator

The Ottawa Hospital

Collaborator

Kingston Health Sciences Centre

Collaborator

University of Saskatchewan

Collaborator

Western University, Canada

Collaborator