Intraoperative Fluid Management Guided by Internal Jugular Vein on Postoperative Complications in Abdominal Surgeries

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-70
SponsorSuez Canal University

About this trial

This study investigates the role of respiratory variation in the internal jugular vein as a tool for intraoperative fluid management during abdominal surgeries under general anesthesia.

The purpose of this clinical trial is to reduce postoperative complications and improve patient outcomes through proper intraoperative fluid management.

The main question it aims to answer is: Can intraoperative fluid management guided by the respiratory variation of the internal jugular vein during abdominal surgeries reduce postoperative complications? Research Hypothesis (Alternative Hypothesis): We hypothesize that fluid management guided by the respiratory variation of the internal jugular vein during abdominal surgeries can reduce postoperative complications.

The patients will be divided into two groups and randomized to receive either intraoperative fluid therapy guided by the respiratory variation of the internal jugular vein or standard fluid therapy. Postoperative complications, length of hospital stay, total amount of fluid administered intraoperatively, use of vasopressors in both groups, and incidence of hypotensive episodes will be recorded.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients' American Society of Anesthesiologists physical status (ASA) is I and II.

The target age group is 20 to 70 years old.

Patients scheduled for abdominal surgery under general anesthesia with normal renal function.

Disqualifiers

Refusal of the procedure or participation in the study.

Coagulopathy.

Pre-existing cardiac, renal, and respiratory diseases. 4-Internal jugular vein thrombosis

Trial design

Design model

Parallel

Treatments tested in this trial

  • Respiratory variation of the Internal Jugular Vein (IJV)

    Diagnostic test

    In the study group, the fluid therapy will be guided by the respiratory variation (RV) of the Internal Jugular Vein (IJV) throughout surgery. Fluid maintenance will be continued as long as the IJV diameter is less than 2 cm and the IJV RV is more than 18. If the IJV diameter exceeds 2 cm and the IJV RV is less than 18, fluids will be stopped.

Treatment groups

84 Participants
are divided into 2 treatment groups
Group A: Internal Jugular Vein (IJV) group (Study group)Active comparator 1 intervention
Group B: Control groupNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

The primary outcome is the incidence of postoperative complications in both groups, which will be measured by the occurrence of any of the postoperative complications during the first seven postoperative days in both groups

Postoperative complications will include: (i) infections (urinary tract infection, wound infection, sepsis/septic shock) (ii) GI (Ileus, acute bowel obstruction, GI bleeding, abdominal compartment syndrome), (iii) Cardiovascular (deep venous thrombosis, pulmonary embolism, myocardial ischemia or infarction, cardiac arrest), (iv) Renal (AKI) (v) Respiratory (pneumonia, prolonged mechanical ventilation (more than 24 hours), respiratory failure, ARDS).

Time frame
The first seven postoperative days

Secondary outcomes

1

The length of hospital stay in both groups

Time frame
Up to 30 days postoperatively.
2

Assessment of the total amount of fluid administered intraoperatively in both groups

Time frame
Intraoperatively (From the start to the end of the surgery)
3

Intraoperative vasopressor use in both groups

Time frame
Intraoperatively (From the start to the end of the surgery)
4

Intraoperative hypotensive episodes in both groups

Time frame
Intraoperatively (From the start to the end of the surgery)

Other outcomes

Sponsors and contacts

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