Health TrialsbyHealthPanel

Investigating the Effects of Green Tea on Blood Viscosity

ConditionCardiovascular Disease
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65+
SponsorUniversity of Reading

About this trial

A diet high in flavonoids is becoming more established as beneficial to human health. Recent data suggest that the regular consumption of flavanols can reduce the numbers of deaths by cardiovascular disease at a population level. The mechanisms for these reductions in deaths by cardiovascular disease are still debated and little is known about their impacts on factors affecting blood viscosity. The metabolism of flavanols is complex, with different metabolites being predominant in the blood at different time points. Therefore, in this study, we will investigate the effects of green tea, a well-known source of flavanols, on blood viscosity at different time points. This will be assessed in healthy individuals with no history of cardiovascular disease aged 65+ years old. Blood viscosity will be measured before, and 2hours and 8hours after the consumption of green tea.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Participants ages 65 years and older

Non-smoker Participants with at least 2 'good' veins for giving blood

Disqualifiers

Participants under (BMI <18.5 kg/m2) or extremely over-nourished (BMI >30 kg/m2)

Participants on prescription medication for CVD or regularly taking blood thinning drugs such as aspirin.

Participants with a history of CVD or CVD in immediate family/ high resting blood pressure

Participants with any food allergies/intolerances

Trial design

Design model

Crossover

Treatments tested in this trial

  • Green Tea

    Dietary supplement

    200 mL Green Tea

  • Control (Hot Water)

    Dietary supplement

    200 mL hot water

Treatment groups

35 Participants
are divided into 2 treatment groups
Group A: Green TeaExperimental treatment 2 interventions
Group B: Hot WaterPlacebo comparator 2 interventions

Trial outcomes

Primary outcomes

1

Whole Blood Viscosity

Time frame
Baseline to 2 hours and 8 hours

Secondary outcomes

1

Plasma Viscosity

Time frame
Baseline to 2 hours and 8 hours
2

Blood Triglycerides

Time frame
Baseline to 2 hours and 8 hours
3

C-reactive protein

Time frame
Baseline to 2 hours and 8 hours

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Reading

Lead sponsor

Biotechnology and Biological Sciences Research Council

Collaborator

Royal Berkshire NHS Foundation Trust

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: