The study aims to investigate visuospatial abilities and psychological outcomes in patients with multiple scleroris (MS) and patients with West Nile virus infection (vWN). Patients will undergo a specific neuropsychological and psychological evaluation. Afterwards, patients will receive 10 sessions of cognitive training integrating digital exercises and prismatic lenses. At the end of the treatment, patients will be re-evaluated to explore for potential changes in the cognitive and psychological profile.
Diagnosis of: Multiple Scleroris OR vWN infection ascertained by laboratory analysis and received no later than twelve months prior to the date of hospitalization
preserved use of at least one hand
normal or corrected to normal vision
history of psychiatric and/or concurrent neurological diseases
inability to provide informed consent,
impaired comprehension of oral instructions,
Parallel
Mindlenses Professional
DeviceMindLenses professional's device combines the prismatic adaptation (PA) procedure with the administration of serious games (SG) for cognitive training using a tablet
Conventional rehabilitation
BehavioralConventional rehabilition consists in computerized exercises focused on the main cognitive domains
Measure of changes in cognitive performance after the treatment
Cognitive performances will be assessed by a full neuropsychological battery encompassing the main cognitive domain, such as memory, attention, executive function, language, visuospatial abilities. Specific neuropsychological tests will be defined on the basis of the specific neurological population. Raw scores at each test and scale will be converted in z-scores based on each test/scale normative data. Z-scores will be averaged to calculate composite scores specific for each cognitive domain and for motor functioning. In detail, the composite scores will be the following: general cognitive functioning, attention, executive function, short-term memory, long-term memory, visuospatial abilities, language.
Measure of changes in psychological aspects after the treatment
Psychological measures will be administered to investigate the presence of anxiety and depression in each patient. Questionnaires will be scored based on published norms.
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