About this trial
Lumbar disc herniations may result in lower limb weakness. In such cases, there is a strong indication for surgical intervention through microdiscectomy. This clinical study aims to investigate preoperative factors that may influence the postoperative outcomes of patients undergoing this procedure.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients suffering from lower limb paresis (motor deficit) caused by lumbar disk herniation undergoing a single-level microdiskectomy
Age (years) > 17
Disqualifiers
Age (years) < 18
Medical history of lumbar spine surgery
Absence of limb paresis
Motor deficit caused by other than disk herniation aetiologies
Trial population
Patients visiting the three recruitment hospitals, all located in North Greece.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Muscle Strength
The strength of lower main muscles will be assessed and will be rated according to the Medical Research Council Scale for Muscle Strength. The scale takes values between 0 and 5, with 5 being the best possible (healthy).
Duration of paresis before surgical treatment
Time between the initiation of paresis and surgical treatment measured in days
Secondary outcomes
Age
The age of participant as measured in years
Obesity
Body Mass Index (BMI) measured as the ratio between the mass measured in kilograms over the square of height measured in meters. There will be two groups of patients: a) with obesity and b) without obesity.
Diabetes Melitus
Participant is diagnosed with diabetes melitus (yes/no)
Hernia location
Categorisation of hernia location based on Magnetic Resonance Imaging (MRI) to a) central, b) subarticular, c) foraminal, and d) extra-foraminal.
Sponsors and contacts
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Aristotle University Of Thessaloniki
Lead sponsor
Hippocration General Hospital
Collaborator
General Hospital of Kavala
Collaborator
European Interbalkan Medical Center
Collaborator