Investigations Into Sepsis-associated Acute Kidney Injury
ConditionAcute Kidney Injury
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-100
SponsorUniversity Hospital of North Norway
About this trial
In this study the investigators would like to study systemic and regional disturbances in patients with sepsis-associated acute kidney injury and in healthy controls undergoing laparoscopic abdominal surgery. Specifically study metabolic, hemodynamic and oxygen transport variables.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Sepsis diagnosed or suspected
Normal premorbid serum creatinine measured or anticipated (if data are not available)
Normovolemia as indicated by a pulse pressure variation less than 12%
Previously healthy individuals scheduled for laparoscopic colon cancer resection
Disqualifiers
None
Trial population
Intensiv care patients Surgical patients
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
Para Aminohippurate
DrugMeasurements of renal plasma flow and glomerular filtration rate
Treatment groups
20 Participants
are divided into 2 treatment groupsGroup A: Sepsis patients1 intervention
Group B: Surgical patients1 intervention
Trial outcomes
Primary outcomes
1
Hemodynamics
Systemic and regional hemodynamics
Time frame
Repeated measures at 10am, 12am, 2pm, 4pm,6pm, and 8pmSecondary outcomes
1
Metabolic alterations
Renal arginine metabolism
Time frame
Repeated measures at 10am, 12am, 2pm, 4pm,6pm, and 8pmSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov