Is BMI Outdated in TKA Patient Selection? Assessment of the Impact of Pre-tubercular Subcutaneous Tissue Thickness and the Risk of Postoperative Infection Following Total Knee Arthroplasty

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorEast Lancashire Hospitals NHS Trust

About this trial

While Body Mass Index (BMI) is currently used as a primary tool for risk stratification in patients undergoing Total Knee Athroplasty(TKA), its limitations raise concerns regarding its accuracy and fairness in guiding surgical decision-making. In particular, reliance on BMI alone may lead to the exclusion of patients who could safely benefit from surgery, while failing to identify others at increased risk due to unfavourable local anatomical factors. Pre-tubercular subcutaneous fat thickness (PTFT) offers a simple, reproducible, and anatomically relevant measurement that directly reflects the soft tissue envelope at the operative site. As such may provide a more clinically meaningful assessment of infection risk than BMI. This study aims to evaluate the association between PTFT and postoperative infection following TKA. By doing so, it seeks to determine whether PTFT could serve as an adjunct or alternative risk stratification tool in clinical practice.

The findings of this study have the potential to inform a more individualized approach to patient selection and preoperative counselling, improving shared decision-making and resource utilisation.

Eligibility criteria

Qualifiers

Adults aged 18 years or older at the time of surgery

Underwent primary total knee replacement surgery

Procedure performed at East Lancashire Hospitals NHS Trust (Burnley General Hospital or Royal Blackburn Hospital)

Surgery performed between 1 November 2023 and 30 November 2024

Disqualifiers

Patients who underwent revision knee replacement surgery

Patients who underwent partial (unicompartmental) knee replacement surgery

Patients aged under 18 years at the time of surgery

Primary procedure performed outside East Lancashire Hospitals NHS Trust

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

400 Participants
are grouped into 1 trial group

Locations

This trial has no locations